Clinical Papers
Male Oxidative Stress Infertility (MOSI): Proposed Terminology and Clinical Practice Guidelines for Management of Idiopathic Male Infertility. Agarwal A, Parekh N, Panner Selvam MK, Henkel R, Shah R, Homa ST, Ramasamy R, Ko E, Tremellen K, Esteves S., et al. World J Mens Health. 2019 May 8. PMID: 31081299
High levels of oxidation-reduction potential in frozen-thawed human semen are significantly correlated with poor post-thaw sperm quality. Saleh R, Elsuity M, Henkel R, Agarwal A. Andrologia. 2020 Apr 30. PMID: 32352588
The effect of oxidative and reductive stress on semen parameters and functions of physiologically normal human spermatozoa. Manesh Kumar Panner Selvam, Ashok Agarwal, Ralf Henkel, Renata Finelli, Kathy Amy Robert, Concetta Iovine, Saradha Baskaran. Free Radic Biol Med. 2020 Mar 9. PMID: 32165282
Multi-center evaluation of oxidation-reduction potential by the MiOXSYS in males with abnormal semen. Ashok Agarwal, Manesh Kumar Panner Selvam, Mohamed Arafa, Hiroshi Okada, Sheryl Homa, Aideen Killeen, Basak Balaban, Ramadan Saleh, Abdullah Armagan, Shubhadeep Roychoudhury, Suresh Sikka. Asian Journal of Andrology. 2019 April 16. PMID: 31006711
A Comparison Between Two Assays for Measuring Seminal Oxidative Stress and their Relationship with Sperm DNA Fragmentation and Semen Parameters. Sheryl T. Homa, Anna M. Vassiliou, Jesse Stone, Aideen P. Killeen, Andrew Dawkins, Jingyi Xie, Farley Gould, and Jonathan W. A. Ramsay. Genes. 2019 Mar 19;10(3). PMID: 30893955
Oxidation-reduction potential and sperm DNA fragmentation, and their associations with sperm morphological anomalies amongst fertile and infertile men. Majzoub A, Arafa M, Mahdi M, Agarwal A, Al Said S, Al-Emadi I, El Ansari W, Alattar A, Al Rumaihi K, Elbardisi H. Arab J Urol. 2018 Feb 1;16(1):87-95. Epub 2018 Mar 16. PMID: 29713539
Oxidation-reduction potential as a new marker for oxidative stress: Correlation to male infertility. Agarwal A, Bui AD. Investig Clin Urol. 2017 Nov;58(6):385-399. PMID: 29124237
A multicenter study to evaluate oxidative stress by oxidation–reduction potential, a reliable and reproducible method. Agarwal A., Arafa M., Chandrakumar R., Majzoub A., AlSaid S., Elbardisi H. Andrology.2017 Jun 9. Epub 2017 Jul 20. PMID: 28726302
Semen quality and infertility status can be identified through measures of oxidation–reduction potential. Arafa M., Agarwal A., Al Said S., Majzoub A., Sharma R., Bjugstad KB., AlRumaihi K., Elbardisi H. Andrologia. 2017 Aug 3 Epub 2017 Aug 3. PMID: 28771782
Clinical Relevance of Oxidation-Reduction Potential in the Evaluation of Male Infertility. Ashok Agarwal and Siew May Wang. Urology. 2017 Jun;104:84-89. Epub 2017.02.016. PMID:28214572
Diagnostic application of oxidation-reduction potential assay for measurement of oxidative stress: clinical utility in male factor infertility. Agarwal A, Roychoudhury S, Sharma R, Gupta S, Majzoub A, Sabanegh E. Reprod Biomed Online. 2017 Jan;34(1):48-57. Epub 2016 Oct 20 PMID: 27839743
Oxidation-reduction potential of semen: what is its role in the treatment of male infertility? Agarwal A, Roychoudhury S, Bjugstad KB, Cho CL. Ther Adv Urol. 2016; 8(5):302-318. PMID: 27695529.
MiOXSYS: A novel method of measuring oxidation reduction potential in semen and seminal plasma. Agarwal A, Sharma R, Roychoudhury S, Du Plessis S, Sabanegh E. Fertil Steril. 2016 Sep 1;106(3):566-573.e10 Epub 2016 May 31. PMID: 27260688.